The Best Bed Bug Spray

Photo: Eco Defense Bed Bug Killer - Bed Bug Spray & Dust Mite Spray - Natural Treatment - 16 Oz

UPDATED DECEMBER 14, 2025

To help you find the perfect bed bug spray, we continuously put forth the effort to update and expand our list of recommendable bed bug sprays. Our team collects, edits and publishes new information, in order to present it to you in an accurate, significant and neatly arranged way.

Photo: Eco Defense Bed Bug Killer - Bed Bug Spray & Dust Mite Spray - Natural Treatment - 16 Oz

Our Picks

Harris Toughest Killer

Tough Formula: Formulated for maximum strength, this Black Label bed bug spra...

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Premo Guard Killer Spray

NATURAL. Made from natural ingredients. Use for entire home, farm, yard, trav...

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Eco Defense Killer

KILLS ON CONTACT - Natural ingredients eliminate bed bugs on contact in all s...

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Our Choice

Harris Toughest Killer

Tough Formula: Formulated for maximum strength, this Black Label bed bug spra...

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Premo Guard Killer Spray

NATURAL. Made from natural ingredients. Use for entire home, farm, yard, trav...

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Low Price

Eco Defense Killer

KILLS ON CONTACT - Natural ingredients eliminate bed bugs on contact in all s...

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7 More Bed Bug Spray Alternatives

SC Johnson Raid Foaming Spray

Kills bed bugs and their eggs on contact

Kills bed bugs on surfaces for up to 4 weeks

Foam expands into hard to reach indoor places, and is easy to see where you sprayed

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HARRIS White Label Killer

TOUGH FORMULA: Formulated for maximum strength, this Black Label bed bug spray is a pow...

KILLS BED BUGS, EGGS, AND PYRETHOID-RESISTANT STRAINS: Effectively eliminates all life ...

LONG-LASTING RESIDUAL PROTECTION: Provides extended control for up to 16 weeks after ap...

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Ortho Home Defense Max

Kill bed bugs, bed bug eggs, fleas and ticks with Ortho Home Defense Max Bed Bug, Flea ...

This bed bug spray kills even the toughest bed bugs (pyrethroid-resistant bed bugs)

Use this indoor bug killer as a spot treatment around bed frames, baseboards and mattre...

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United Industries Ecologic Killer

KILLS BED BUGS BY CONTACT: Aerosol spray kills bed bugs by contact, including pyrethroi...

TREAT CRACKS AND CREVICES: Apply as a spot treatment to cracks and crevices around base...

TREAT MATTRESSES: Use on mattresses, box springs, bed frames and luggage as listed.

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Hygea Natural Extra Strength & Mite Natural Travel Spray

Bed bug exterminator: Our natural bed bug killer spray is for home DIY or Our formula e...

Odorless & stain-free: Hygea Natural's unique formula can be used on any surface includ...

Child & Pet friendly : The Formula powerfully exterminates bed bugs & pests. This bed b...

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BASF PT Alpine Flea & Killer

Quick Results: Fast knockdown of bed bugs and fleas, providing fast relief and long-las...

Long-lasting Control: Lasting effectiveness on multiple surfaces for up to 3 weeks; Aid...

Reduced Risk Active Ingredient: Dinotefuran, approved for public health use and food ha...

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Colton's Naturals Natural Mite Killer Spray

Rapid-Acting Multi-Mite Elimination — Mite Killer Spray. Our advanced spray formula tar...

Pet- & Family-Friendly Non-Toxic Formula — Mite repellent spray. Formulated with safe, ...

Kills all stages of the Mite Lifecycle— Kills both the living mites and their Larvae (e...

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Buying Guide

Top Rated Bed Bug Sprays

If you're looking into finding the best rated bed bug spray, you should probable check out the Harris Toughest Killer. We looked at various sources of reviews and found this one to have the best mix between review count and average rating stars.

Harris Toughest Killer

The Lowest Price We Could Find

Often, going for the best price is a simple but good option. With a price of $10.89 (last checked this morning), we do not list any other bed bug sprays cheaper than the SC Johnson Raid Foaming Spray. Just remember that it's not always the best option to go for the cheapest one.

SC Johnson Raid Foaming Spray

The Bed Bug Spray With the Most Reviews

With at least 2291 reviews and counting, the Eco Defense Killer might be another option to consider. This large amount of reviews signalizes that many people are using it, with most of them beeing satisfied.

Eco Defense Killer

High Quality Bed Bug Sprays

It's quite rare that the saying "You get what you pay for" turns out incorrect. If you have the money on the sideline, feel free to choose the most expensive item from our list: The Harris Toughest Killer currently sells for $59.99.

The Bed Bug Spray With the Most Clicks

If you trust us and our users, feel free to check out the Harris Toughest Killer. Our statistics say that it is the most favorite Bed Bug Spray from the list above.

Our Bestseller

If you're still undecided, I would recommend that you go with the masses and choose the top selling bed bug spray: The Ortho Home Defense Max is the hottest bestseller in this category right now.

Ortho Home Defense Max

Bed Bug Spray Reviews

There are no reviews on bed bug sprays, yet.

Be the first to write a review, or check for additional reviews in the Further Reading section below.

Research

Do you want to know more about bed bug sprays? Check out the links below to gain knowledge about the whole topic of bed bug spray products.

Efficacy of an essential oil-based pesticide for controlling bed bug (Cimex lectularius) infestations in apartment buildings

… there is only one scientific report documenting the efficacy of 25(b) bed bug sprays … cedar oil + 2% sodium lauryl sulfate; Reneotech, North Bergen, NJ, USA) and Bed Bug Patrol (0.03 … Nine of the 11 tested products caused 0%–61% mortality in direct spray laboratory assays …

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About this Article

This page about Bed Bug Sprays was composed by V. Tobies and published by Alternative.me.
It was last updated on 2025-12-14 08:48:25 and has been viewed 5003 times.